Lipid profile and thyroid hormone concentrations in children with epilepsy treated with oxcarbazepine monotherapy: a prospective long-term study
Background and purpose: To evaluate prospectively the changes and possible asso- ciations in lipid and thyroid profiles in children treated with oxcarbazepine (OXC) monotherapy. Methods: Serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL- C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TGs), lipoprotein (a) [Lp(a)], free thyroxine (FT4), free triiodothyronine (FT3), thyrotropin (TSH) and gamma-glutamyltransferase (GGT) concentrations […]
Associations between obesity, adverse behavioral patterns and cardiovascular risk factors among adolescent inhabitants of a Greek island
Background: Excess weight, unhealthy lifestyle habits and their sequelae have become a well-recognized public health problem in most countries. The objective of the study was to examine the relationship of adolescent over- weight/obesity with behavioral habits and their associa- tion with blood pressure (BP) and lipid profile. Methods: Anthropometric parameters, lifestyle, BP and lipid profile […]
Comparing calculated LDL-C with directly measured LDL-C in healthy and in dyslipidemic children
Background: LDL-C is one of the strongest markers for atherosclerosis and therapeutic decisions in children are based on its levels. Friedewald formula (FF) which is usually used for the calculation of LDL-C (cLDL-C); and Anandaraja’s formula (AF) may under- or overestimate actual levels. Objective: To compare cLDL-C with directly measured LDL-C (dLDL-C) as a screening […]
Serum antibodies against Oxidized LDL in Children and Adolescents with and without Hypercholesterolemia
Background: The oxidative modification of LDL (oxLDL) appears to play a key role in the early developmental stages of atherosclerosis. Increased serum antibodies against the oxLDL (anti-oxLDL antibodies) have been found in adults with atherosclerotic diseases, as well as in healthy ones. However, the clinical significance and its precise role, atherogenic or atheroprotective, have not […]